Antimicrobial and Antioxidant activity of Copper Nanoparticles Synthesised from Centella asiatica

Abstract

Copper nanoparticles can be synthesised using various methods, including chemical reduction, thermal decomposition, and green synthesis approaches. The present study focuses on the green synthesis of copper oxide nanoparticles from the leaf extract of Centelia asiatica. The synthesised copper nanoparticles were characterised by a UV-visible spectrophotometer, which gave an optical absorbance spectrum at 204.8 nm, and by X-ray diffraction, Bragg's reflection 2e was 30.334°. The synthesised copper nanoparticles exhibited good antimicrobial activity against pathogenic strains of Bacillus velezensis, Klebsiella ozaenae, Pseudomonas aeruginosa, and Proteus vulgaris, with the minimum inhibitory concentration of Bacillus velezensis and Proteus vulgaris being 0.6 µg/ml. The copper nanoparticles showed antioxidant activity with the DPPH method and the FRAP reducing assay.